The Concept of CMR
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- October 22, 2009
- Joint associations of adiposity and physical activity with mortality: the National Institutes of Health-AARP Diet and Health Study. Am J Epidemiol 2009;169:1344-51
- Koster A, Harris TB, Moore SC, Schatzkin A, Hollenbeck AR, van Eijk JT, Leitzmann MF.
Description of this Publication
This study evaluates whether physical activity protects against the adverse affects of high adiposity. This question was examined in the National Institutes of Health-AARP Diet and Health Study which involved 185,412 men and women aged 51-72 years followed for 10 years. Overweight, obesity, an elevated waist circumference and low physical activity were all independent predictors of mortality. Compared to normal-weight physically active individuals, mortality risks were 1.62 (95% CI: 1.50-1.75) for sedentary normal-weight subjects, 1.79 (95% CI: 1.37-2.33) for active morbidly obese individuals and 3.45 (95% CI: 2.79-4.00) for sedentary morbidly obese persons. Respective mortality risks if waist circumference substitutes for body mass index were 1.61 (95% CI: 1.48-1.76), 1.44 (95% CI: 1.23-1.68) and 2.01 (95% CI: 1.74-2.32). Therefore, physical activity attenuated the increased mortality risk associated obesity or abdominal obesity but did not completely eliminate such risk.
Key Words
Obesity,
Abdominal Obesity / Body Fat Distribution,
Physical Activity/Exercise