The Concept of CMR
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- February 16, 2010
- Impact of metabolic syndrome compared with impaired fasting glucose on the development of type 2 diabetes in a general Japanese population: the Hisayama study. Diabetes Care. 2009;32:2288-93
- Mukai N, Doi Y, Ninomiya T, Hata J, Yonemoto K, Iwase M, Iida M, Kiyohara Y.
Description of this Publication
The purpose of the present study was to examine the association between metabolic syndrome and the development of type 2 diabetes in a Japanese population. A total of 1,935 nondiabetic subjects aged 40-79 years were followed prospectively for a mean of 11.8 years. During the follow-up, 286 subjects developed type 2 diabetes. The present study found that metabolic syndrome identified by the clinical criteria of NCEP-ATP III was an independent risk factor for the development of type 2 diabetes in both sexes even after controlling for confounding variables. Furthermore, metabolic syndrome and impaired fasting glucose each independently increased the risk of type 2 diabetes and the coexistence of both conditions increased even more the risk of developing type 2 diabetes. These results suggest that metabolic syndrome is a valuable tool to identify Japanese individuals at high risk of type 2 diabetes.
Key Words
Diabetes,
Metabolic Syndrome