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April 26, 2010
Anthropometric assessment of abdominal obesity and coronary heart disease risk in men: the PRIME study. Heart 2010;96:136-40
Gruson E, Montaye M, Kee F, Wagner A, Bingham A, Ruidavets JB, Haas B, Evans A, Ferrières J, Ducimetière PP, Amouyel P, Dallongeville J.

Description of this Publication

This prospective study was conducted to compare the association between waist-to-height ratio, waist circumference and waist-to-hip ratio and coronary risk. The cohort included 10 602 men, aged 50-59 years, from the Prospective Epidemiological Study of Myocardial Infarction (PRIME). During the 10 years of follow-up, 659 incident coronary events (CHD) were recorded. The results of the present study showed that waist-to-height ratio was positively associated with coronary risk and that this association was slightly more pronounced than waist circumference and waist-to-hip ratio. Moreover, the association remained statistically significant for waist-to-height ratio after adjustment for history of diabetes, systolic and diastolic blood pressure, triglycerides and HDL cholesterol, whereas it was no longer significant for waist-to-hip ratio, waist circumference and body mass index. The authors explain the results by suggesting that the waist-to-height ratio might be a better indicator of visceral adipose tissue than waist circumference. These findings suggest that the waist-to-height ratio is a marginally better predictor of coronary risk, but that the magnitude of difference is probably not clinically important.


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Key Words
Epidemiology, Abdominal Obesity/Body Fat Distribution, Documentation Centre