International Chair on Cardiometabolic Risk

Date	Categories	Title	Author	Format
July 30, 2010	Abdominal Obesity / Body Fat Distribution Ectopic Fat	Why are we shaped differently, and why does it matter?	Michael Jensen, MD, Division of Endocrinology and Metabolism, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN, USA	Expert Opinions Video 0:40 min. (3 MB)
July 23, 2010	Diabetes Prevention Abdominal Obesity / Body Fat Distribution	What are the current recommendations for the management of patients at risk for type 2 diabetes?	Edward Horton, Director of Clinical Research, Joslin Diabetes Center, Boston, MA, USA	Expert Opinions Video 2:11 min. (11 MB)
July 16, 2010	Obesity Metabolism Insulin Resistance	What evidence do we have that systemic CB1 receptors are important in the pathophysiology of glycemia?	Vincenzo Di Marzo, PhD, Istituto di Chimica Biomolecolare Pozzuoli (NA), Italy	Expert Opinions Video 0:35 min. (3 MB)
July 09, 2010	Physical Activity/Exercise Nutrition Childhood Obesity	Where should we focus our prevention efforts: in schools?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 0:38 min. (3 MB)
July 02, 2010	Lipids/Lipoproteins Cardiovascular Disease	Why do elevated HDL cholesterol concentrations not protect against cardiovascular disease?	Arnold von Eckardstein, MD Institute of Clinical Chemistry, University Hospital of Zurich and Center for Integrative Human Biology, University of Zurich, Zurich, Switzerland	Expert Opinions Video 1:40 min. (8 MB)
June 25, 2010	Lipids/Lipoproteins	Are we ready to measure apolipoprotein B in clinical practice?	Chris Packard, DSc, FRSE, Research Director, North Glasgow University Hospital, Professor of Vascular Biochemistry, University of Glasgow, Glasgow, UK	Expert Opinions Video 0:32 min. (2 MB)
June 18, 2010	Nutrition	How should the consumption of healthy foods be promoted?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 1:02 min. (5 MB)
June 11, 2010	Cardiovascular Disease Lipids/Lipoproteins	What are the best therapeutic options to improve HDL functions?	Arnold von Eckardstein, MD Institute of Clinical Chemistry, University Hospital of Zurich and Center for Integrative Human Biology, University of Zurich, Zurich, Switzerland	Expert Opinions Video 1:08 min. (6 MB)
June 04, 2010	Abdominal Obesity / Body Fat Distribution Genetics	Could you comment on the fat storage capacity of different abdominal fat compartments?	André Tchernof, PhD Molecular Endocrinology and Oncology Research Centre, Laval University Medical Research Centre, Québec, QC, Canada	Expert Opinions Video 0:55 min. (4 MB)
May 28, 2010	Cardiovascular Disease Lipids/Lipoproteins Nutrition	Should nutritional supplements be recommended?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 0:52 min. (4 MB)
May 21, 2010	Cardiovascular Disease Lipids/Lipoproteins	What is the relationship between HDL and the endothelium?	Arnold von Eckardstein, MD Institute of Clinical Chemistry, University Hospital of Zurich and Center for Integrative Human Biology, University of Zurich, Zurich, Switzerland	Expert Opinions Video 1:12 min. (6 MB)
May 14, 2010	Cardiovascular Disease Lipids/Lipoproteins	Could you clarify the role of macrophages and the importance of angiogenesis?	Renu Virmani, MD CVPath Institute, Gaithersburg, MD, USA	Expert Opinions Video 1:59 min. (10 MB)
May 07, 2010	Abdominal Obesity / Body Fat Distribution Adipokines Adipose Tissue	With regards to the endocrine properties of adipose tissue, which fat compartment is responsible for the hypoadiponectinemia found in obese subjects?	André Tchernof, PhD Molecular Endocrinology and Oncology Research Centre, Laval University Medical Research Centre, Québec, QC, Canada	Expert Opinions Video 1:20 min. (6 MB)
April 30, 2010	Diabetes Cardiovascular Disease	What is the status of PPAR-alpha agonists as targets for type 2 diabetes and cardiovascular disease?	Bart Staels, PhD Department of Atherosclerosis, Institut Pasteur de Lille, UMR545 Inserm, University of Lille 2, Lille, France	Expert Opinions Video 0:41 min. (3 MB)
April 30, 2010	Clinical Trials Cardiovascular Disease Hypertension	In the ONTARGET study, how do you explain the disconnect between the blood pressure-lowering effects of combined therapy and the lack of further reduction in CVD events?	Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain	Expert Opinions Video 0:48 min. (4 MB)
April 16, 2010	Lipids/Lipoproteins Cardiovascular Disease	Why could apolipoprotein B be better than LDL cholesterol in evaluating the success of therapy?	Chris Packard, DSc, FRSE, Research Director, North Glasgow University Hospital, Professor of Vascular Biochemistry, University of Glasgow, Glasgow, UK	Expert Opinions Video 0:44 min. (3 MB)
April 09, 2010	Cardiovascular Disease Clinical Trials Nutrition	What are the key features of a cardioprotective diet?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 2:05 min. (10 MB)
April 01, 2010	Ectopic Fat Abdominal Obesity / Body Fat Distribution Metabolism: Animal Studies	Does CB1 activation affect ectopic fat accumulation?	Vincenzo Di Marzo, PhD, Istituto di Chimica Biomolecolare Pozzuoli (NA), Italy	Expert Opinions Video 1:07 min. (5 MB)
March 26, 2010	Lipids/Lipoproteins	What is the potential benefit of HDL cholesterol infusion?	H. Bryan Brewer Jr. MD, Director, Lipoprotein and Atherosclerosis Research, MedStar Research Institute, Cardiovascular Research Institute, Washington, DC, USA	Expert Opinions Video 1:05 min. (4 MB)
March 19, 2010	Cardiovascular Disease Lipids/Lipoproteins Diabetes	What simple lipid targets would you recommend in clinical practice?	Christie Ballantyne, MD, FACC, FACP, Director, Center for Cardiovascular Disease Prevention, Chief Section of Atherosclerosis and Vascular Medicine, Methodist DeBakey Heart Center and Baylor College of Medicine, Houston, TX, USA	Expert Opinions Video 0:34 min. (2 MB)
March 12, 2010	Lipids/Lipoproteins Cardiovascular Disease	Could you summarize the protective roles of HDL particles? Do high HDL levels confer greater protection?	Arnold von Eckardstein, MD Institute of Clinical Chemistry, University Hospital of Zurich and Center for Integrative Human Biology, University of Zurich, Zurich, Switzerland	Expert Opinions Video 1:19 min. (5 MB)
March 05, 2010	Steroid Hormones	What about the effects of HRT on quality of life?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 1:20 min. (7 MB)
February 26, 2010	Cardiovascular Disease Thrombosis	What is the importance of hemorrhage in the natural progression of plaques?	Renu Virmani, MD CVPath Institute, Gaithersburg, MD, USA	Expert Opinions Video 0:37 min. (3 MB)
February 19, 2010	Abdominal Obesity / Body Fat Distribution Adipose Tissue Gender Differences	What is the importance of adipocyte size?	André Tchernof, PhD Molecular Endocrinology and Oncology Research Centre, Laval University Medical Research Centre, Québec, QC, Canada	Expert Opinions Video 1:29 min. (7 MB)
February 12, 2010	Steroid Hormones	What are the current indications for HRT?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 1:05 min. (5 MB)
February 05, 2010	Clinical Trials Hypertension	From the ONTARGET study results, does the method used to reduce blood pressure matter in terms of its impact on cardiovascular events?	Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain	Expert Opinions Video 1:19 min. (7 MB)
January 29, 2010	Lipids/Lipoproteins Cardiovascular Disease	Why could apolipoprotein B be better than cholesterol in estimating cardiovascular disease risk?	Chris Packard, DSc, FRSE , Research Director, North Glasgow University Hospital, Professor of Vascular Biochemistry, University of Glasgow, Glasgow, UK	Expert Opinions Video 0:49 min. (4 MB)
January 22, 2010	Cardiovascular Disease Clinical Trials	Is the debate over regarding the harmful cardiovascular effects of HRT in post-menopausal women?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 1:09 min. (6 MB)
January 15, 2010	Adipose Tissue Metabolism	What are the effects of CB1 activation on adipocytes?	Vincenzo Di Marzo, PhD, Istituto di Chimica Biomolecolare Pozzuoli (NA), Italy	Expert Opinions Video 0:49 min. (4 MB)
January 08, 2010	Lipids/Lipoproteins Clinical Trials Cardiovascular Disease	Are better drugs available to raise HDL cholesterol?	H. Bryan Brewer, Jr., MD, Director, Lipoprotein and Atherosclerosis Research, MedStar Research Institute, Cardiovascular Research Institute, Washington, DC, USA	Expert Opinions Video 1:23 min. (5 MB)
January 05, 2010	Lipids/Lipoproteins Insulin Resistance Cardiovascular Disease	In which patients should we measure apolipoprotein B?	Christie Ballantyne, MD, FACC, FACP, Director, Center for Cardiovascular Disease Prevention, Chief Section of Atherosclerosis and Vascular Medicine, Methodist DeBakey Heart Center and Baylor College of Medicine, Houston, TX, USA	Expert Opinions Video 0:47 min. (3 MB)
December 18, 2009	Diabetes Lipids/Lipoproteins Cardiovascular Disease	Could there be a link between HDL and diabetes?	Arnold von Eckardstein, MD Institute of Clinical Chemistry, University Hospital of Zurich and Center for Integrative Human Biology, University of Zurich, Zurich, Switzerland	Expert Opinions Video 1:23 min. (5 MB)
December 11, 2009	Cardiovascular Disease	Why do we need to improve the current atherosclerosis classification?	Renu Virmani, MD CVPath Institute, Gaithersburg, MD, USA	Expert Opinions Video 1:01 min. (5 MB)
December 04, 2009	Abdominal Obesity / Body Fat Distribution Adipose Tissue Ectopic Fat	What are the differences between the subcutaneous fat compartment and the intra-abdominal fat compartment?	André Tchernof, PhD Molecular Endocrinology and Oncology Research Centre, Laval University Medical Research Centre, Québec, QC, Canada	Expert Opinions Video 1:01 min. (5 MB)
November 27, 2009	Adipokines Lipids/Lipoproteins Metabolism: Animal Studies	Do you think that the relationship between adiponectin and HDL is mediated by this adipokine's effect on the liver?	Bart Staels, PhD Department of Atherosclerosis, Institut Pasteur de Lille, UMR545 Inserm, University of Lille 2, Lille, France	Expert Opinions Video 0:57 min. (5 MB)
November 20, 2009	Cardiovascular Disease Hypertension Abdominal Obesity / Body Fat Distribution	Can we really prevent renal disease or do we only delay its complications?	Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain	Expert Opinions Video 0:54 min. (4 MB)
November 13, 2009	Lipids/Lipoproteins Cardiovascular Disease	Do you believe that the small, dense LDL phenotype is independently predictive of an increased risk of cardiovascular disease?	Chris Packard, DSc, FRSE, Research Director, North Glasgow University Hospital, Professor of Vascular Biochemistry, University of Glasgow, Glasgow, UK	Expert Opinions Video 0:36 min. (3 MB)
November 06, 2009	Cardiovascular Disease Steroid Hormones	What is the status of cardiovascular prevention in post-menopausal women?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 1:15 min. (6 MB)
October 30, 2009	Lipids/Lipoproteins Metabolism Cardiovascular Disease	Where does HDL cholesterol come from?	H. Bryan Brewer Jr. MD, Director, Lipoprotein and Atherosclerosis Research, MedStar Research Institute, Cardiovascular Research Institute, Washington, DC, USA	Expert Opinions Video 1:04 min. (4 MB)
October 23, 2009	Lipids/Lipoproteins	Can LDL size be measured in clinical practice?	Christie Ballantyne, MD, FACC, FACP, Director, Center for Cardiovascular Disease Prevention, Chief Section of Atherosclerosis and Vascular Medicine, Methodist DeBakey Heart Center and Baylor College of Medicine, Houston, TX, USA	Expert Opinions Video 0:34 min. (2 MB)
October 16, 2009	Diabetes Cardiovascular Disease	Could you comment on the heterogeneity of risk in type 2 diabetic patients?	Arnold von Eckardstein, MD Institute of Clinical Chemistry, University Hospital of Zurich and Center for Integrative Human Biology, University of Zurich, Zurich, Switzerland	Expert Opinions Video 1:03 min. (4 MB)
October 09, 2009	Cardiovascular Disease Lipids/Lipoproteins	Why is it important to understand the process of atherosclerosis?	Renu Virmani, MD CVPath Institute, Gaithersburg, MD, USA	Expert Opinions Video 1:21 min. (6 MB)
October 02, 2009	Abdominal Obesity / Body Fat Distribution	What is the biological nature of visceral fat?	André Tchernof, PhD Molecular Endocrinology and Oncology Research Centre, Laval University Medical Research Centre, Québec, QC, Canada	Expert Opinions Video 0:38 min. (3 MB)
September 25, 2009	Metabolism: Animal Studies Metabolism: Human Studies	Could you comment on the status of PPARγ and β/δ?	Bart Staels, PhD Department of Atherosclerosis, Institut Pasteur de Lille, UMR545 Inserm, University of Lille 2, Lille, France	Expert Opinions Video 1:04 min. (6 MB)
September 21, 2009	Obesity Weight Loss	Does obesity surgery work for everybody?	Arya Sharma, MD, FRCPC, Professor of Medicine and Chair for Obesity Research and Management, University of Alberta, Canada	Expert Opinions Video 0:51 min. (3 MB)
July 10, 2009	Cardiovascular Disease Hypertension Metabolic Syndrome	What is the link between abdominal obesity and renal disease?	Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain	Expert Opinions Video 1:13 min. (6 MB)
July 03, 2009	Diabetes Ectopic Fat Lipids/Lipoproteins	Could you comment on the role of hepatic fat accumulation as a potential contributing factor to the development of type 2 diabetes?	Chris Packard, DSc, FRSE , Research Director, North Glasgow University Hospital, Professor of Vascular Biochemistry, University of Glasgow, Glasgow, UK	Expert Opinions Video 0:40 min. (3 MB)
June 26, 2009	Gender Differences Cardiovascular Disease	What is unique about cardiovascular risk in women?	Barbara V. Howard, PhD, Medstar Research Institute, Washington, DC, USA	Expert Opinions Video 0:35 min. (3 MB)
June 17, 2009	Abdominal Obesity / Body Fat Distribution Insulin Resistance Metabolism	What is the key player in cardiometabolic changes: intra-abdominal obesity or 2-AG levels?	Vincenzo Di Marzo, PhD, Istituto di Chimica Biomolecolare Pozzuoli (NA), Italy	Expert Opinions Video 1:10 min. (5 MB)
May 22, 2009	Cardiovascular Disease Lipids/Lipoproteins	In secondary prevention patients, is HDL cholesterol still important if LDL cholesterol is low?	H. Bryan Brewer, Jr., MD, Director, Lipoprotein and Atherosclerosis Research, MedStar Research Institute, Cardiovascular Research Institute, Washington, DC, USA	Expert Opinions Video 0:35 min. (2 MB)
May 15, 2009	Cardiovascular Disease Clinical Trials Inflammation	Based on the JUPITER results, is hs-CRP a cause or marker of cardiovascular disease?	Andrew M. Tonkin, MBBS, MD, MRACP, FRACP, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia	Expert Opinions Video 1:00 min. (4 MB)
May 08, 2009	Cardiovascular Disease Clinical Trials Inflammation	What do trials such as JUPITER and SEARCH add to the literature on the benefits of statin therapy?	Christopher P. Cannon, MD, Associate Professor of Medicine, Harvard Medical School, Cardiovascular Division, Brigham & Women’s Hospital, Boston, MA, USA	Expert Opinions Video 0:57 min. (4 MB)
April 24, 2009	Adipose Tissue Metabolic Syndrome Metabolism	Is there a renewed interest in the role of adipose tissue in the pathophysiology of the metabolic syndrome?	Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden	Expert Opinions Video 0:50 min. (2 MB)
April 17, 2009	Abdominal Obesity / Body Fat Distribution Cardiovascular Disease Cardiometabolic Risk	Is there a need for a global cardiometabolic risk algorithm?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 0:41 min. (2 MB)
April 09, 2009	Adipokines Adipose Tissue Inflammation	The endocrine function of adipose tissue has been an exciting development. However, there is a plethora of 'adipokines'. Which ones are getting closer to prime time and why?	Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden	Expert Opinions Video 1:09 min. (3 MB)
April 03, 2009	Clinical Trials Lipids/Lipoproteins	What is the rationale for combination therapy in the treatment of dyslipidemia?	H. Bryan Brewer, Jr., MD, Director, Lipoprotein and Atherosclerosis Research, MedStar Research Institute, Cardiovascular Research Institute, Washington, DC, USA	Expert Opinions Video 1:02 min. (2 MB)
March 27, 2009	Abdominal Obesity / Body Fat Distribution Adipokines Cardiovascular Disease	How do you see the contribution of hypoadiponectinemic state of visceral obesity in the modulation of global cardiometabolic risk?	Arya Sharma, MD, FRCPC, Professor of Medicine and Chair for Obesity Research and Management, University of Alberta, Edmonton, Canada	Expert Opinions Video 0:49 min. (1 MB)
March 20, 2009	Hypertension Metabolic Syndrome	Could you comment on how the presence/absence of the metabolic syndrome affects the management of patients with hypertension?	Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain	Expert Opinions Video 2:04 min. (7 MB)
March 13, 2009	Abdominal Obesity / Body Fat Distribution Adipose Tissue Inflammation	How do you see the mobilization of fat cells?	Max Lafontan, PhD, Research Director, INSERM, Laboratoire de Recherche sur les Obésités, U858, Institut de Médecine Moléculaire de Rangueil, Toulouse, France	Expert Opinions Video 2:08 min. (7 MB)
March 06, 2009	Diabetes Nutrition Physical Activity/Exercise	Is it possible to implement a lifestyle modification program in clinical practice?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 2:22 min. (7 MB)
February 27, 2009	Abdominal Obesity / Body Fat Distribution Lipids/Lipoproteins Metabolic Syndrome	What is the mechanism for the low HDL cholesterol levels in patients with abdominal obesity and the metabolic syndrome?	Philip J. Barter, MD, MBBS, FRACP, PhD, Professor and Director, the Heart Research Institute, Sydney, Australia	Expert Opinions Video 1:35 min. (3 MB)
February 20, 2009	Abdominal Obesity / Body Fat Distribution Cardiovascular Disease	What is the key message from the INTERHEART study?	Luc Van Gaal, MD, PhD, Professor of Medicine, Antwerp University Hospital, Faculty of Medicine, Department of Diabetology, Metabolism & Clinical Nutrition, Antwerp, Belgium	Expert Opinions Video 1:01 min. (3 MB)
February 13, 2009	Adipose Tissue Inflammation Insulin Resistance	Your own work has focused on the cytokine IL-6. How important is adipose tissue in the production/effect of that cytokine in abdominal obesity? Is this cytokine atherogenic and diabetogenic?	Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden	Expert Opinions Video 1:15 min. (3 MB)
February 06, 2009	Adipokines Adipose Tissue Cardiovascular Disease	How exciting for you is the discovery of adiponectin?	Arya Sharma, MD, FRCPC, Professor of Medicine and Chair for Obesity Research and Management, University of Alberta, Edmonton, Canada	Expert Opinions Video 0:57 min. (2 MB)
January 30, 2009	Cardiovascular Disease Metabolic Syndrome	How do you see global CVD risk assessment in the future?	Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain	Expert Opinions Video 2:18 min. (7 MB)
January 23, 2009	Adipose Tissue Obesity	What are the next steps in the biology of adipose tissue?	Max Lafontan, PhD, Research Director, INSERM, Laboratoire de Recherche sur les Obésités, U858, Institut de Médecine Moléculaire de Rangueil, Toulouse, France	Expert Opinions Video 1:19 min. (4 MB)
January 16, 2009	Abdominal Obesity / Body Fat Distribution Prevention	Can we measure waist circumference in clinical practice? Does it make a difference?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 1:36 min. (5 MB)
January 09, 2009	Abdominal Obesity / Body Fat Distribution Ethnicity Metabolic Syndrome	How much progress has been made in the development of screening tools to identify individuals with features of the metabolic syndrome in the Asian population?	Juliana Chan, MD, FRCP, Professor of Medicine and Therapeutics, Director, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China	Expert Opinions Video 1:14 min. (3 MB)
January 05, 2009	Cardiovascular Disease Lipids/Lipoproteins Metabolic Syndrome	What is the role of low HDL cholesterol in the elevated CHD risk of metabolic syndrome patients?	Philip J. Barter, MD, MBBS, FRACP, PhD, Professor and Director, the Heart Research Institute, Sydney, Australia	Expert Opinions Video 0:58 min. (2 MB)
December 19, 2008	Abdominal Obesity / Body Fat Distribution	Could you comment on waist circumference measurement variability?	Luc Van Gaal, MD, PhD, Professor of Medicine, Antwerp University Hospital, Faculty of Medicine, Department of Diabetology, Metabolism & Clinical Nutrition, Antwerp, Belgium	Expert Opinions Video 0:46 min. (2 MB)
December 12, 2008	Adipose Tissue Diabetes Documentation Centre	Do you see a primary defect in the adipose tissue of individuals with a strong family history of diabetes or should we look elsewhere?	Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden	Expert Opinions Video 1:05 min. (3 MB)
December 05, 2008	Abdominal Obesity / Body Fat Distribution Adipose Tissue	Could you comment on the role played by expanded visceral adipose tissue as an endocrine organ?	Arya Sharma, MD, FRCPC, Professor of Medicine and Chair for Obesity Research and Management, University of Alberta, Edmonton, Canada	Expert Opinions Video 0:49 min. (2 MB)
November 28, 2008	Hypertension Insulin Resistance Metabolic Syndrome	Could you comment on the fact that about 50% of hypertensive patients have insulin resistance whereas the other half do not show evidence of insulin resistance?	Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain	Expert Opinions Video 1:01 min. (2 MB)
November 21, 2008	Adipose Tissue Ectopic Fat Documentation Centre	What is the right amount of fat?	Stephen O'Rahilly, MD, FRCP, FRS, Head of Department and Professor of Clinical Biochemistry and Medicine, University of Cambridge, Cambridge, UK	Expert Opinions Video 1:14 min. (4 MB)
November 14, 2008	Adipokines Adipose Tissue Inflammation	Could you comment on the biology of adipose tissue?	Max Lafontan, PhD, Research Director, INSERM, Laboratoire de Recherche sur les Obésités, U858, Institut de Médecine Moléculaire de Rangueil, Toulouse, France	Expert Opinions Video 1:30 min. (5 MB)
November 07, 2008	Cardiovascular Disease Clinical Cardiology	Considering the strengths and limitations of carotid IMT measurement, what have we learned from it regarding CVD factors: confirmatory findings or new factors/markers?	John J. Kastelein, MD, Professor of Medicine and Chairman of the Department of Vascular Medicine at the University of Amsterdam, Amsterdam, The Netherlands	Expert Opinions Video 0:53 min. (2 MB)
October 31, 2008	Cardiometabolic Risk Cardiovascular Disease Metabolic Syndrome	What can the family doctor do to assess global cardiometabolic risk?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 1:40 min. (5 MB)
October 24, 2008	Abdominal Obesity / Body Fat Distribution Ethnicity Metabolic Syndrome	Is there evidence for population differences in the relationship of waist circumference to visceral fat deposition?	Juliana Chan, MD, FRCP, Professor of Medicine and Therapeutics, Director, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China	Expert Opinions Video 0:48 min. (2 MB)
October 17, 2008	Abdominal Obesity / Body Fat Distribution Cardiovascular Disease	Visceral obesity has been shown to be the atherogenic/diabetogenic form of obesity. Why are we still talking about weight and BMI?	John D. Brunzell, MD, Professor of Medicine-Emeritus, active, University of Washington, Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, Seattle, WA, USA	Expert Opinions Video 1:17 min. (2 MB)
October 10, 2008	Acute Coronary Syndromes Clinical Trials Lipids/Lipoproteins	What are the approaches to increase HDL cholesterol?	H. Bryan Brewer, Jr., MD, Director, Lipoprotein and Atherosclerosis Research, MedStar Research Institute, Cardiovascular Research Institute, Washington, DC, USA	Expert Opinions Video 2:36 min. (6 MB)
October 03, 2008	Cardiovascular Disease Lipids/Lipoproteins Metabolic Syndrome	Why is it important to raise HDL cholesterol levels?	Philip J. Barter, MD, MBBS, FRACP, PhD, Professor and Director, the Heart Research Institute, Sydney, Australia	Expert Opinions Video 0:46 min. (1 MB)
September 26, 2008	Abdominal Obesity / Body Fat Distribution Cardiovascular Disease Diabetes	Could you comment on the importance of measuring waist circumference beyond BMI to properly identify high-risk patients?	Luc Van Gaal, MD, PhD, Professor of Medicine, Antwerp University Hospital, Faculty of Medicine, Department of Diabetology, Metabolism & Clinical Nutrition, Antwerp, Belgium	Expert Opinions Video 1:08 min. (3 MB)
September 19, 2008	Abdominal Obesity / Body Fat Distribution Metabolic Syndrome Metabolism	Do you think that omental fat per se plays a role in the pathophysiology of the metabolic syndrome or is it just a marker of "dysfunctional" adipose tissue?	Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden	Expert Opinions Video 0:37 min. (1 MB)
September 15, 2008	Abdominal Obesity / Body Fat Distribution Diabetes Insulin Resistance	What is the role of adipose tissue function in the overall "dysmetabolic" profile found in abdominally obese type 2 diabetic patients?	Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden	Expert Opinions Video 1:14 min. (3 MB)
September 05, 2008	Abdominal Obesity / Body Fat Distribution Obesity	How can we assess visceral obesity in clinical practice?	John D. Brunzell, MD, Professor of Medicine-Emeritus, active, University of Washington, Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, Seattle, WA, USA	Expert Opinions Video 0:53 min. (3 MB)
August 29, 2008	Cardiometabolic Risk	What are the anti-inflammatory properties of HDL?	H. Bryan Brewer, Jr., MD, Director, Lipoprotein and Atherosclerosis Research, MedStar Research Institute, Cardiovascular Research Institute, Washington, DC, USA	Expert Opinions Video 1:16 min. (2 MB)
September 07, 2007	Cardiovascular Disease	Is there a role for new markers in clinical practice?	Christie Ballantyne, MD, FACC, FACP, Director, Center for Cardiovascular Disease Prevention, Chief Section of Atherosclerosis and Vascular Medicine, Methodist DeBakey Heart Center and Baylor College of Medicine, Houston, TX, USA	Expert Opinions Video 0:37 min. (2 MB)
September 07, 2007	Abdominal Obesity / Body Fat Distribution Metabolic Syndrome Thrombosis	Does the thrombosis/fibrinolysis component of the metabolic syndrome receive enough consideration in clinical practice?	Luc Van Gaal, MD, PhD, Professor of Medicine, Antwerp University Hospital, Faculty of Medicine, Department of Diabetology, Metabolism & Clinical Nutrition, Antwerp, Belgium	Expert Opinions Video 1:22 min. (5 MB)
September 07, 2007	Cardiovascular Disease Diabetes Metabolic Syndrome	Is the cardiometabolic risk profile of type 2 diabetic patients significantly worse than it was 10 years ago?	Luc Van Gaal, MD, PhD, Professor of Medicine, Antwerp University Hospital, Faculty of Medicine, Department of Diabetology, Metabolism & Clinical Nutrition, Antwerp, Belgium	Expert Opinions Video 1:08 min. (5 MB)
September 07, 2007	Abdominal Obesity / Body Fat Distribution Hypertension Metabolic Syndrome	Could you discuss managing hypertension among patients with visceral obesity and the metabolic syndrome?	Arya Sharma, MD, FRCPC, Professor of Medicine and Chair for Obesity Research and Management, University of Alberta, Edmonton, Canada	Expert Opinions Video 1:02 min. (3 MB)
September 07, 2007	Abdominal Obesity / Body Fat Distribution Adipose Tissue Hypertension	What is the link between visceral obesity and hypertension? Are factors other than hyperinsulinemia involved?	Arya Sharma, MD, FRCPC, Professor of Medicine and Chair for Obesity Research and Management, University of Alberta, Edmonton, Canada	Expert Opinions Video 1:00 min. (4 MB)
September 07, 2007	Abdominal Obesity / Body Fat Distribution Physical Activity/Exercise Weight Loss	The metabolic syndrome of visceral obesity: is it overconsumption of calories or lack of physical activity?	Robert Ross, PhD, Professor, School of Kinesiology and Health Studies, Department of Medicine, Division of Endocrinology and Metabolism, Queen's University, Kingston, ON, Canada	Expert Opinions Video 2:13 min. (7 MB)
September 07, 2007	Abdominal Obesity / Body Fat Distribution Ectopic Fat Lipids/Lipoproteins	Could you comment on the respective importance of visceral adiposity vs. liver fat with regard to elevated cardiometabolic risk?	Robert Ross, PhD, Professor, School of Kinesiology and Health Studies, Department of Medicine, Division of Endocrinology and Metabolism, Queen's University, Kingston, ON, Canada	Expert Opinions Video 1:26 min. (5 MB)
September 07, 2007	Abdominal Obesity / Body Fat Distribution Obesity	Does measuring waist circumference add to information provided by BMI in clinical practice?	Robert Ross, PhD, Professor, School of Kinesiology and Health Studies, Department of Medicine, Division of Endocrinology and Metabolism, Queen's University, Kingston, ON, Canada	Expert Opinions Video 1:04 min. (3 MB)
September 07, 2007	Cardiovascular Disease Lipids/Lipoproteins	What is the usefulness of apo B in clinical practice?	Göran Walldius, MD, PhD, Professor, King Gustaf V Research Institute, Karolinska Institute, Stockholm, Medical Director, Cardiovascular Unit, Marketing at AstraZeneca AB, Södertälje, Sweden	Expert Opinions Video 0:36 min. (2 MB)
September 07, 2007	Diabetes Ethnicity Prevention	Which measures should be prioritized when assessing and managing cardiometabolic risk in Asia?	Juliana Chan, MD, FRCP, Professor of Medicine and Therapeutics, Director, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China	Expert Opinions Video 1:47 min. (6 MB)
September 07, 2007	Cardiovascular Disease Lipids/Lipoproteins Metabolic Syndrome	What is the importance of HDL?	H. Bryan Brewer, Jr., MD, Director, Lipoprotein and Atherosclerosis Research, MedStar Research Institute, Cardiovascular Research Institute, Washington, DC, USA	Expert Opinions Video 1:09 min. (4 MB)
September 07, 2007	Abdominal Obesity / Body Fat Distribution Metabolic Syndrome	Can a consensus be reached regarding the key elements of the metabolic syndrome?	Philip J. Barter, MD, MBBS, FRACP, PhD, Professor and Director, the Heart Research Institute, Sydney, Australia	Expert Opinions Video 1:09 min. (4 MB)
September 07, 2007	Acute Coronary Syndromes Inflammation Lipids/Lipoproteins	What are the anti-inflammatory properties of HDL?	Philip J. Barter, MD, MBBS, FRACP, PhD, Professor and Director, the Heart Research Institute, Sydney, Australia	Expert Opinions Video 1:17 min. (4 MB)
September 06, 2007	Abdominal Obesity / Body Fat Distribution Cardiovascular Disease Diabetes	Is abdominal obesity important in CVD risk assessment and management in type 2 diabetes?	Marja-Riitta Taskinen, MD, PhD, Professor of Medicine, University of Helsinki, Department of Medicine, Biomedicum, Helsinki, Finland	Expert Opinions Video 1:34 min. (5 MB)
September 06, 2007	Cardiovascular Disease Diabetes Lipids/Lipoproteins	Which features of type 2 diabetes dyslipidemia contribute to CVD risk and which features of the dyslipidemic state should we target for optimal management of CVD risk in type 2 diabetes?	Marja-Riitta Taskinen, MD, PhD, Professor of Medicine, University of Helsinki, Department of Medicine, Biomedicum, Helsinki, Finland	Expert Opinions Video 1:56 min. (6 MB)
September 06, 2007	Diabetes Ectopic Fat Lipids/Lipoproteins	Could you comment on the mechanism responsible for type 2 diabetes hypertriglyceridemia?	Marja-Riitta Taskinen, MD, PhD, Professor of Medicine, University of Helsinki, Department of Medicine, Biomedicum, Helsinki, Finland	Expert Opinions Video 1:31 min. (5 MB)
September 06, 2007	Cardiovascular Disease Diabetes Lipids/Lipoproteins	What is the typical dyslipidemia of type 2 diabetes?	Marja-Riitta Taskinen, MD, PhD, Professor of Medicine, University of Helsinki, Department of Medicine, Biomedicum, Helsinki, Finland	Expert Opinions Video 1:05 min. (3 MB)
September 06, 2007	Cardiovascular Disease Diabetes Metabolic Syndrome	Could you comment on the heterogeneity of CVD risk in type 2 diabetes patients?	Marja-Riitta Taskinen, MD, PhD, Professor of Medicine, University of Helsinki, Department of Medicine, Biomedicum, Helsinki, Finland	Expert Opinions Video 1:05 min. (3 MB)
September 06, 2007	Abdominal Obesity / Body Fat Distribution Hypertension Insulin Resistance	What is the link between visceral adiposity, insulin resistance, and hypertension?	Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain	Expert Opinions Video 0:50 min. (3 MB)
September 01, 2007	Physical Activity/Exercise Ectopic Fat Adipose Tissue	Could you comment on the importance of having a normal adipose tissue mass?	Max Lafontan, PhD, Research Director, INSERM, Laboratoire de Recherche sur les Obésités, U858, Institut de Médecine Moléculaire de Rangueil, Toulouse, France	Expert Opinions Video 1:11 min. (4 MB)
September 01, 2007	Abdominal Obesity / Body Fat Distribution Ectopic Fat	Is visceral obesity a marker of ectopic fat distribution?	Stephen O'Rahilly, MD, FRCP, FRS, Head of Department and Professor of Clinical Biochemistry and Medicine, University of Cambridge, Cambridge, UK	Expert Opinions Video 0:56 min. (3 MB)
September 01, 2007	Adipose Tissue Metabolic Syndrome Obesity	Should we redefine what constitutes obesity? Is it excess adipose tissue mass or rather dysfunctional adipose tissue?	Stephen O'Rahilly, MD, FRCP, FRS, Head of Department and Professor of Clinical Biochemistry and Medicine, University of Cambridge, Cambridge, UK	Expert Opinions Video 1:11 min. (4 MB)
September 01, 2007	Adipokines Ectopic Fat Metabolic Syndrome	What are the clinical implications of the dysmetabolic profile of lipodystrophic patients? How does this affect the key causes of the metabolic syndrome?	Stephen O'Rahilly, MD, FRCP, FRS, Head of Department and Professor of Clinical Biochemistry and Medicine, University of Cambridge, Cambridge, UK	Expert Opinions Video 1:26 min. (5 MB)
September 01, 2007	Adipose Tissue Cardiovascular Disease Inflammation	What is the relationship between an inflammatory state and atherosclerotic plaques?	Peter Libby, MD, Mallinckrodt Professor of Medicine, Harvard Medical School and Chief, Cardiovascular Medicine, Brigham & Women's Hospital, Boston, MA, USA	Expert Opinions Video 1:31 min. (5 MB)
September 01, 2007	Cardiovascular Disease Clinical Trials Inflammation	Do you believe it is important to measure CRP?	Peter Libby, MD, Mallinckrodt Professor of Medicine, Harvard Medical School and Chief, Cardiovascular Medicine, Brigham & Women's Hospital, Boston, MA, USA	Expert Opinions Video 2:18 min. (8 MB)
September 01, 2007	Adipokines Adipose Tissue Inflammation	What is the importance of adipose tissue as an endocrine organ?	Max Lafontan, PhD, Research Director, INSERM, Laboratoire de Recherche sur les Obésités, U858, Institut de Médecine Moléculaire de Rangueil, Toulouse, France	Expert Opinions Video 2:08 min. (7 MB)
September 01, 2007	Metabolism: Animal Studies Ectopic Fat	Could the endocannabinoid system be a major player in the etiology of liver steatosis?	George Kunos, MD, PhD, Research Scientist, Bethesda, MD, USA	Expert Opinions Video 2:21 min. (8 MB)
September 01, 2007	Cardiovascular Disease Hypertension Metabolism: Animal Studies	Is there evidence for a direct role of endocannabinoids on cardiovascular disease?	George Kunos, MD, PhD, Research Scientist, Bethesda, MD, USA	Expert Opinions Video 2:49 min. (10 MB)
September 01, 2007	Cardiovascular Disease Clinical Cardiology	How feasible do you think it will be to incorporate imaging technologies in the assessment of patients' global CVD risk?	John J. Kastelein, MD, Professor of Medicine and Chairman of the Department of Vascular Medicine at the University of Amsterdam, Amsterdam, The Netherlands	Expert Opinions Video 0:41 min. (2 MB)
September 01, 2007	Abdominal Obesity / Body Fat Distribution Ectopic Fat Metabolic Syndrome	Are visceral obesity, liver fat infiltration, and dysfunctional adipose tissue related?	Scott M. Grundy	Expert Opinions Video 0:46 min. (2 MB)
September 01, 2007	Insulin Resistance Cardiometabolic Risk Lipids/Lipoproteins	Which factors/markers do you think will emerge as key predictors of global CMR beyond the Framingham risk score?	Scott M. Grundy	Expert Opinions Video 0:32 min. (1 MB)
September 01, 2007	Abdominal Obesity / Body Fat Distribution Metabolic Syndrome Physical Activity/Exercise	What role does exercise/physical activity play in the management of abdominal obesity?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 1:46 min. (6 MB)
September 01, 2007	Adipose Tissue Metabolic Syndrome Physical Activity/Exercise	What role does lack of physical activity play in the etiology of the metabolic syndrome?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 0:30 min. (1 MB)
September 01, 2007	Abdominal Obesity / Body Fat Distribution Metabolic Syndrome Physical Activity/Exercise	What is the relationship between physical activity and the metabolic syndrome?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 1:04 min. (4 MB)
September 01, 2007	Cardiovascular Disease Cardiometabolic Risk Metabolic Syndrome	What is cardiometabolic risk, and is it a new term to replace the metabolic syndrome?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 1:16 min. (5 MB)
September 01, 2007	Abdominal Obesity / Body Fat Distribution Cardiovascular Disease Metabolic Syndrome	Does the metabolic syndrome exist?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 1:24 min. (5 MB)
September 01, 2007	Abdominal Obesity / Body Fat Distribution Insulin Resistance Metabolic Syndrome	Is there a distinction to be made between the insulin resistance syndrome and the metabolic syndrome? Are they the same thing?	Jean-Pierre Després, PhD, FAHA, Scientific Director, International Chair on Cardiometabolic Risk, Professor, Division of Kinesiology, Université Laval, Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada	Expert Opinions Video 1:41 min. (7 MB)
September 01, 2007	Ethnicity Metabolic Syndrome Obesity	Do you believe that the metabolic syndrome is as much of an issue in Asia as it is in North America?	Juliana Chan, MD, FRCP, Professor of Medicine and Therapeutics, Director, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China	Expert Opinions Video 0:58 min. (3 MB)
September 01, 2007	Abdominal Obesity / Body Fat Distribution Ethnicity Obesity	There is evidence that BMI values associated with increased type 2 diabetes and CVD risk are lower in Asia than in the rest of the world. Which factors explain this discrepancy? What about the role of visceral adiposity?	Juliana Chan, MD, FRCP, Professor of Medicine and Therapeutics, Director, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China	Expert Opinions Video 0:27 min. (1 MB)
August 31, 2007	Epidemiology Ethnicity Metabolic Syndrome	Could you comment on the epidemic proportions reached by type 2 diabetes in Asia? Is abdominal obesity a factor?	Juliana Chan, MD, FRCP, Professor of Medicine and Therapeutics, Director, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China	Expert Opinions Video 0:30 min. (1 MB)
August 31, 2007	Abdominal Obesity / Body Fat Distribution Adipokines Lipids/Lipoproteins	Which mechanisms are responsible for the link between visceral obesity and atherogenic dyslipidemia?	John D. Brunzell, MD, Professor of Medicine-Emeritus, active, University of Washington, Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, Seattle, WA, USA	Expert Opinions Video 0:57 min. (3 MB)
August 31, 2007	Abdominal Obesity / Body Fat Distribution Lipids/Lipoproteins	What is the atherogenic dyslipidemia of visceral obesity?	John D. Brunzell, MD, Professor of Medicine-Emeritus, active, University of Washington, Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, Seattle, WA, USA	Expert Opinions Video 1:02 min. (3 MB)
August 31, 2007	Cardiovascular Disease Metabolic Syndrome	What is the status of the debate on the metabolic syndrome?	Philip J. Barter, MD, MBBS, FRACP, PhD, Professor and Director, the Heart Research Institute, Sydney, Australia	Expert Opinions Video 0:52 min. (3 MB)
August 31, 2007	Diabetes Obesity Cardiovascular Disease	What are the consequences of the obesity epidemic?	Christie Ballantyne, MD, FACC, FACP, Director, Center for Cardiovascular Disease Prevention, Chief Section of Atherosclerosis and Vascular Medicine, Methodist DeBakey Heart Center and Baylor College of Medicine, Houston, TX, USA	Expert Opinions Video 0:44 min. (2 MB)

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