The PROCAM study showed that HDL cholesterol is an important driver of CHD risk and provided evidence that HDL cholesterol levels exert a much stronger influence on CHD risk in individuals with elevated global cardiovascular risk.
One of the most important findings of the PROCAM study was that CHD risk factors do not act in isolation but rather in conjunction.
The PROCAM study demonstrated that fasting triglyceride levels are an independent risk factor for CHD events, regardless of HDL or LDL cholesterol concentrations.
Evaluation of the association between the first observation and the longitudinal change in C-reactive protein, and all-cause mortality. Heart 2008;94:457-62