The ability of diet to induce a marked caloric deficit, combined with the ability of exercise to maintain muscle mass and readily mobilize fat from the intra-abdominal depot, likely provides the best of both worlds (40, 41). Data from the National Weight Control Registry suggests that individuals who are most successful at attaining and maintaining significant weight loss are likely to use a combination of diet and exercise to achieve their goal (42). Additionally, during weight loss interventions, physical exercise has been shown to improve cardiorespiratory fitness (17, 18), which would be expected to further reduce risk of morbidity and mortality independent of changes in weight and intra-abdominal fat (43, 44). The combination of diet and exercise is therefore the ideal strategy for losing weight and reducing intra-abdominal fat.

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