Obesity is a key determinant of CVD. When compared to normal weight individuals, obese patients have several metabolic complications that increase their CVD risk.
Although much epidemiological evidence has shown that obesity is a major CVD risk factor, not all obese individuals are at increased risk of CVD.
Because of the differences observed among obese individuals, special attention must be paid to body fat distribution and to abdominal adipose tissue accumulation in particular, which usually worsens the metabolic profile of overweight/obese patients.
Evaluation of the association between the first observation and the longitudinal change in C-reactive protein, and all-cause mortality. Heart 2008;94:457-62