The metabolic syndrome is very common in people with diabetes, and those with both diabetes and the metabolic syndrome have the highest rates of coronary heart disease (CHD) (Figure 1) (18). A recent prospective, 5 year community-based study of people with newly diagnosed type 2 diabetes found that the metabolic syndrome increased the risk of CVD events (19). Survival diminished progressively according to how many syndrome features patients displayed. These results confirmed UKPDS (14) findings that hyperglycemia per se may have a limited impact on CVD events in type 2 diabetes when the other features of the metabolic syndrome are taken into consideration (Figure 2).
Patients with type 2 diabetes are much more likely to experience cardiovascular complications. However, the link between diabetes and CVD is complex and not yet fully understood. Beyond the acknowledged impact of hyperglycemia, abdominal obesity-related risk factors may also play a role in the high incidence of cardiovascular events in diabetes.

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