There is a definite gender difference in adipose tissue distribution:
Men accumulate adipose tissue in the intra-abdominal cavity (apple pattern).
Women accumulate adipose tissue in the gluteal/femoral depots (pear pattern).
Intra-abdominal adipose tissue accumulation—the adipose tissue distribution pattern generally found in men—predicts greater obesity-related health risks.
Pre-menopausal women have less intra-abdominal adipose tissue and a more favourable metabolic risk profile than men with similar total body fat. This protection against intra-abdominal (visceral) fat accumulation is lost when women enter menopause.
Evaluation of the association between the first observation and the longitudinal change in C-reactive protein, and all-cause mortality. Heart 2008;94:457-62