The Concept of CMR
Intra-abdominal Adipose Tissue: The Culprit?
Influence of Menopause
- 1Key Points (1 page)
- 2The influence of menopause on adipose tissue distribution (3 pages)
- 3Metabolic consequences of adipose tissue redistribution after menopause (2 pages)
- 4References (1 page)
Key Points
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- Abdominal (visceral) adiposity increases with the onset of menopause.
- Abdominal tissue redistribution with menopause appears to be independent of age and total body fat and could be related to a relative deficit in estrogens.
- Menopause has a negative impact on plasma lipoprotein-lipid levels, which may increase CVD risk.
- HTR in post-menopausal women helps protect against intra-abdominal fat accumulation. However, prospective studies that have assessed “hard” CVD endpoints have failed to confirm HRT’s benefits. Current evidence does not support the use of HRT to reduce menopause-related CVD risk.
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