The Concept of CMR

Key Points

• Obesity and related comorbidities occur when energy intake exceeds energy expenditure over time.
• In sedentary individuals, resting metabolic rate accounts for a large part of total energy expenditure.
• Physical activity increases energy expenditure by increasing resting metabolic rate, enhancing sensitivity to specific hormones, and decreasing post-exercise energy intake.
• Physical activity has the greatest impact on total daily energy expenditure. However, a high level of physical activity is required for this to occur.
• Exercise benefits cardiovascular health and risk factors beyond what can be explained by increased energy expenditure.